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For example, SRSF4 S457 and DDX24 S80 , which are associated with mRNA splicing and alteration of RNA secondary structure, were equally upregulated by ligand in cells with either receptor (Supplemental Figure 2A), while ROCK1 S1336 and RANBP2 S796 , which are associated with cytoskeleton remodeling and cell cycle, were equally downregulated by ligand (Supplemental Figure 2B)

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A statin should be started, regardless of baseline lipid levels, for any patient with diabetes who has overt CVD

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That's why the AHLA warned about miniaturization