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A 6-month, double-blinded, placebo-controlled trial for DPN patients demonstrated that oral ALA (600 mg twice daily) significantly improved neurological symptom scores (NSS), neurological disability scores (NDS), VAS, and VPT compared to placebo

When to talk to your provider Reach out sooner rather than later if youve reached your maintenance dose and notice little to no change in appetite, if side effects are severe enough to interfere with daily life, or if hunger suddenly returns after being well controlled

Electrolytes are also helpful for staying hydrated, and may even be helpful for constipation

Things like individual patient demographics , sticking to the prescribed medication, and lifestyle choices such as diet and exercise are crucial

Vascular endothelial growth factor (VEGF) is a prime inducer of angiogenesis, a procedure of new vessel development