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Tirzepatide and retatrutide are also glucose-dependent insulinotropic polypeptide (GIP) agonists

Finally, ROS are generated after exposure to physical agents (ultraviolet rays and heat) and after chemotherapy and radiotherapy in cancer

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Their work showed that restoring MST1 expression activates p53, which subsequently phosphorylates Drp1 at Ser616 to facilitate mitochondrial fission while concurrently suppresses Parkin transcription (61)

Sanae 2014)