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Soldevila B, Puig-Domingo M

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Interest in such applications is largely driven by their proposed mechanisms of action, including enhancement of tissue repair, modulation of inflammation, and cytoprotective effects observed in preclinical studies

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She started on Mounjaro in April 2024 and continued taking the medication until December, falling from 87kg (13.7st) to 70kg

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The "central plan" of GLP-1 RA is not limited to individual cells, but also achieves the reconstruction of whole-body energy metabolism through the neuroendocrine immune network: GLP-1 receptors are highly expressed in areas such as the hypothalamus and solitary tract nucleus of the brain, and their activation can inhibit the activity of appetite centers (such as NPY/AgRP neurons), while enhancing the transmission of satiety signals (such as POMC neurons)

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