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3.1.2 Role of Nrf2/HO-1 pathway in ferroptosis and antioxidant defense The Nrf2/heme oxygenase-1 (HO-1) pathway plays a central role in oxidative stress-induced ferroptosis

INSULIN STIMULATION: Activates GLP-1 receptors on pancreatic beta-cells stimulates insulin secretion in a GLUCOSE-DEPENDENT manner (only when blood glucose is elevated minimal hypoglycaemia risk) 2