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An observational study performed among 303 participants with and without T2DM who underwent computed tomography (CT) angiography due to chest pain, reported a positive association of endogenous GLP-1 levels with coronary plaque burden (Piotrowski et al., 2013)

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This validates the principle behind combining copper peptide serums with at-home microneedling though at-home results will be more modest than this clinical-grade tattooing technique