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#pharmacology #medicine To view or add a comment, sign in New research highlights the dangers of polypharmacy in chronic pain careshowing high rates of concurrent opioid and sedating medication use

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Human leptin deficiency caused by a missense mutation: multiple endocrine defects, decreased sympathetic tone, and immune system dysfunction indicate new targets for leptin action, greater central than peripheral resistance to the effects of leptin, and spontaneous correction of leptin-mediated defects

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