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Ramezani A, Kheirkhah F, Zabihi E, Shirafkan H, Moudi S

Dietary intake is modest estimated at 100-150 mg/day from fruits, vegetables, and meats and much of this is broken down by digestive enzymes (gamma-glutamyltranspeptidase and dipeptidases) in the intestinal lumen before absorption [1][2]

Disruption of the 12/15-lipoxygenase gene (Alox15) protects hyperlipidemic mice from nonalcoholic fatty liver disease

This is because increased GH may stimulate cell proliferation and cancer progression

Interestingly, Yuki Sato and coworkers indicated that the antioxidant effect of caffeic acid is more potent than chlorogenic acid, and the latter is metabolized into caffeic acid in the intestine