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Patients who lose significant weight on tirzepatide may need lower levothyroxine doses
However, these agents can be expensive for patients whose insurances do not cover the medications
Phase 2 trial data showed up to 24 percent weight loss at 48 weeks, suggesting even more potent effects than either semaglutide or tirzepatide alone
Some plans require something called step therapy, meaning patients have to try and fail on other drugs or treatments before getting covered for the one their doctor wants them to take
No protocol is universally "best." The right choice depends on your history with GLP-1 agonists, your GI sensitivity, your access to appropriate syringes, your willingness to manage reconstitution at lower concentrations, and your goals
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