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Increase in Enterobacteriaceae species, such as Salmonella , Klebsiella , Shigella , and Escherichia , was observed in independent cohorts of European women (Karlsson et al., 2013) and Nordic (Huang et al., 2018) diabetic patients taking metformin

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B12 plays a vital role in the production of white blood cells, which are responsible for fighting off harmful bacteria and viruses