As the popularity of GLP-1 receptor agonists such as Ozempic, Wegovy, and Zepbound increases, a newly reported complication known as Ozempic feet has become a growing concern
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AMPK-mediated phosphorylation of BECN1(beclin 1) promotes ferroptosis by inhibiting SLC7A11 activity or inducing autophagy [109, 110] whereas AMPK-mediated phosphorylation of ACACA suppresses ferroptosis by inhibiting fatty acid biosynthesis [111]
