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Pietrocola F, Galluzzi L, Bravo-San Pedro JM, Madeo F, Kroemer G

By this point, many individuals on GLP-1 therapies achieve at least a 5% reduction in body weight

This faster regain could be because people using drugs dont need to consciously practise changing their diet to lose weight, so when they stop taking the medication, they might not have developed the practical strategies that could help them keep it off, said senior author and Oxford associate professor Dimitrios Koutoukidis in an official statement

Recent FDA warnings in 2025 have highlighted increased concerns about counterfeit versions and compounded formulations of these medications