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Nature 631 , 627634 (2024)

Pflaum, M., & Ruman, R

Research has documented their role in promoting blood vessel genesis, reducing fibrotic scarring, and supporting recovery from neurological injury

Presumably opioid receptor activation involves generally similar conformational changes but, considering the remarkably deep solvent-exposed binding pocket that is characteristic of opioid receptors, one might anticipate interesting surprises in the effects of structurally distinct agonists