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Molecules can cross the tight junctions via two distinct size-selective and charge-selective paracellular pathways: the pore pathway and the leak pathway

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Conclusions In this large real-world cohort of patients with type 2 diabetes and pre-existing aortic aneurysm, GLP-1RA therapy was associated with significantly lower risks of aortic rupture/dissection, hypertensive crisis, and all-cause mortality compared with DPP-4i therapy

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