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The metabolic parameters, systemic inflammatory markers, one-carbon metabolism products, ultrasound and histological improvement were evaluated at baseline (T0M) and after 12 months from LSG (T12M)

In addition, women in the treatment arm ( n = 85) were supplemented daily with 3 g of LC orally (day-3 until day of first positive pregnancy test), while those in the control arm (n = 85) received a placebo

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This innovative approach achieved a high yield of over 70 wt% GO, with more than 90% of the flakes being monolayer