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The surgery was performed on the right hind limb and the left limb served as a control

In the ELIXA and the EXSCEL trials, GLP-1RAs (once daily lixisenatide and once weekly exenatide, respectively) didnt provide benefit in MACE reduction compared to placebo, but were non-inferior to placebo for the primary composite outcome of MACE

In patients with type 2 diabetes inadequately controlled on metformin immediate-release alone, the overall incidence of adverse reactions of hypoglycemia was 1.3% in patients given add-on sitagliptin and 2.1% in patients given add-on placebo

Experiment 2: oral doseresponse study of Atlas987 with a fixed oral dose of paroxetine During the course of the experiment of batch #1, we lost two rats after the oral injection