dpp 4 inhibitors and glp 1 vs GLP-1 receptor agonists or DPP-4 inhibitors: How to guide the clinician? The Role of GLP-1, DPP-4, – Discovery and development of dipeptidyl

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Vegan and vegetarian diet rich in fruits and vegetables are commonly associated with a gut microbiome signature enriched in bacteria like Lachnospiraceae, Butyricicoccus and Roseburia hominis which specialize in breaking down SCFAs (6568)

doi: 10.3389/fnagi.2025.1601602 Received 28 March 2025 Accepted 03 July 2025 Published 24 July 2025 Volume 17 - 2025 Edited by Rita Machado De Olivera, New University of Lisbon, Portugal Reviewed by Venkateswarlu Kanamarlapudi, Swansea University Medical School, United Kingdom Joon W Shim, Marshall University, United States Updates Copyright 2025 Li, Huang, Wang, Huang, Shi, Luo and Huang

Integrative pharmacology and experimental validation have identified 48 bioactive components in SMI that target the PPAR/SIRT1/PGC-1 signaling pathway (Yang et al., 2024)