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This process accelerates the connective tissue degradation mediated by histone proteases and consequently induces joint disease (31, 118)

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Bioorg Med Chem Lett 14(13):34513455 Keillor JW, Menard A, Castonguay R et al (2004) Pre-steady-state kinetic studies of rat kidney gamma-glutamyl transpeptidase confirm its ping-pong mechanism

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