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The two compounds are widely co-investigated in pulsatile growth hormone release research, where the GHRH analogue and GHRP are studied for their complementary mechanisms at the somatotroph

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The chronic subcutaneous administration of Ex-4 attenuates the peripheral symptoms of type 2 diabetes in rats, including hyperglycemia and IR, and enhances the levels of brain cortical GLP-1 and insulin-like growth factor (IGF)-1 and their downstream signaling pathways