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This is a preview of subscription content, access via your institution Access options Access Nature and 54 other Nature Portfolio journals Get Nature+, our best-value online-access subscription $32.99 / 30 days cancel any time Subscribe to this journal Receive 12 digital issues and online access to articles $119.00 per year only $9.92 per issue Rent or buy this article Prices vary by article type from$1.95 to$39.95 Prices may be subject to local taxes which are calculated during checkout References Laman Trip, D
High-risk features at baseline: Prior symptomatic gallstones or biliary colic Existing asymptomatic stones on prior imaging Obesity (BMI 35), particularly in female patients over 40 Rapid prior weight loss history Crohn's disease or terminal ileal resection (impairs bile salt reabsorption) Family history of cholelithiasis Patients with prior symptomatic gallstones should discuss prophylactic cholecystectomy with a surgeon before starting semaglutide, or at minimum have a baseline ultrasound documented in the chart
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