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doi: 10.3389/fmicb.2022.871645

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The key transcription factors that regulate gene expression are NF-E2-related factor 2 (Nrf2) via the antioxidant response element (ARE), AP-1, and nuclear factor kappa B (NF-B)

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, Nrf2 is a critical regulator of the innate immune response and survival during experimental sepsis

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