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Treatment typically involves immunosuppressive medications such as corticosteroids, thiopurines, methotrexate, or biologic therapies (anti-TNF agents, vedolizumab, ustekinumab)

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As we learn more about the antiinflammatory properties of incretin-based therapies, it becomes likely that they could be effective across a wide spectrum of diseases

demonstrated that the E3 ubiquitin-protein ligase TRIM3 functions as a tumor suppressor by degrading SLC7A11, thereby inhibiting the tumorigenesis of non-small cell lung cancer (NSCLC) [24]