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The molecule cycles between its reduced (GSH) and oxidized (GSSG) forms, donating electrons to neutralize reactive oxygen species (ROS) either directly or through glutathione peroxidase-catalyzed reactions
O'Brien S, Kantarjian H, Koller C, Feldman E, Beran M, Andreeff M , Giralt S, Cheson B, Keating M, Freireich E, Rios MB, Talpaz M
In some cases, the physiological underpinnings overlap, which indicates that some of the therapies used to treat IBD can be just as effective for IBS
The liver is the organ with the highest glutathione concentration in the human body
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