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In one study, treatment with carnitine preparations (4000 mg/day over a period of one week) improved the symptoms of fatigue and normalized blood carnitine levels in most subjects who had undergone chemotherapy

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People report decreased appetite as early as one week, and significantly less hunger, reduced eating, and fewer cravings starting between weeks 3 and 8

Int J Mol Sci 25(11):5571 Nah EH, Choi YJ, Cho S, Park H, Kim S, Kwon E, Cho HI (2024) Changes in nonalcoholic fatty liver disease and M2BPGi due to lifestyle intervention in primary healthcare