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Recent researches have further examined the effects of melatonin supplementation and circadian factors on NS workers

Oxidative stress is characterized by excess reactive oxygen species that overwhelm endogenous antioxidant defenses and significantly contribute to endothelial dysfunction in ED [9]

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Our results also reveal mitochondrial iron overload via HO-1 mitochondrial translocation as a key mechanism as well as a potential molecular target for oxidative stress-induced ferroptosis in cardiomyocytes