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Physicians who prescribe unapproved drugs without an Investigational New Drug (IND) application violate federal law and risk medical board sanctions

They are not approved by the FDA for human use outside of clinical trials and are not legally sold as dietary supplements or over-the-counter drugs

Originally developed and FDA-approved for treating HIV-associated lipodystrophy (excess visceral fat), tesamorelin has since gained traction in bodybuilding for its ability to: Elevate IGF-1 levels, enhancing muscle protein synthesis and recovery Reduce visceral and subcutaneous fat, leading to a leaner physique Preserve lean muscle mass, especially during calorie deficits Support tissue repair, collagen turnover, and joint health In short, tesamorelin acts as a growth hormone booster that creates an anabolic environment favorable for bodybuilders chasing fat loss, recovery, and physique enhancement

MOTS-c vs Tesamorelin: Key Research Differences MOTS-c and Tesamorelin represent two distinct research categories MOTS-c is a mitochondrial-derived peptide studied for its role in cellular energy signaling

View at PubMed Falutz J, Allas S, Blot K, et al