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However, research from both independent and industry-sponsored studies has revealed that most HTP users in Japan also smoke cigarettes.[ix] [x] One study showed that for two-thirds of these dual users, HTP use allowed them to reduce the number of cigarettes they smoked.[xi] But for many of this group, switching completely was not their ultimate goal, with the same study finding 52% of those using HTP said they replaced some of the cigarettes they consumed with HTP so that they did not have to completely give up smoking
A large U.S
It is mostly localized to the enteric nervous system
Nicotine use can affect brain development in young people under 25 and increase their risk of future addiction
