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Inhaling caffeine is not an approved or well studied delivery method and may pose cardiovascular risks

8,9 Such measures could act synergistically with the availability of effective alternative nicotine products like vaping devices for smokers who are unable or unwilling to stop using nicotine products

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Bulky cystic lesions with thick walls predominantly located in the upper lobes are also apparent, which may correspond to emphysema with fibrosis or AEF (Fig