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This was confirmed in three cohort studies that reported duration,385090 and Pope et al 2011 concluded that the steep association with cigarettes per day did not materially change when duration was allowed for in the Cancer Prevention Study II study.10 In another study,50 the relative risk for less than 10 years smoking duration was 1.73, compared with 2.51 for 30-40 years duration, representing 48% of the excess relative risk (and these relative risks had been adjusted for number of cigarettes smoked per day)

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