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Abbreviations AUC: Area under the curve CMS: Cigarette Management System CO: Carbon monoxide FDA: Food and Drug Administration IRB: Institutional review board ITP: Investigational Tobacco Product NRT: Nicotine replacement therapy REDCap: Research Electronic Data Capture RNC: Reduced nicotine content SES: Socioeconomic status TCA: Family Smoking Prevention and Tobacco Control Act TCORS: Tobacco Center of Regulatory Science UNC: Usual nicotine content References Benowitz NL, Henningfield JE

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This Surgeon General's report on smoking cessation, the 34th report on smoking and health since 1964, was compiled using a longstanding, peer-reviewed, and comprehensive process to safeguard the scientific rigor and practical relevance of Surgeon General's reports on tobacco