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Thord Hassler, Vice President for Research and Development, says despite efforts in the U.S

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Consistent with nicotines anti-inflammatory effects, chronic nicotine administration via an osmotic minipump did not increase either TNF- or IL-1 in the nucleus accumbens in male mice (160), thereby supporting the notion that the constituents in the JUUL pods, or the interaction of nicotine with the constituents, led to the changes in inflammatory markers

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