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Additionally, since there were few never-smoking adults who used ECs, the ability to detect significant associations with respiratory symptoms may have been limited, calling for future research to seek out larger samples of adults who use ECs but never-smoked cigarettes

Cigarette smoking evolved as a convenience product for busy modern life

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The findings indicate that a former smoker who quits at age 40 would generally need about 1015 years of abstinence to reduce their cardiovascular mortality risk to that of someone who has never smoked ( 43 )

Frequent monitoring and adjustments of the dosages of these medications may be needed