where did tobacco come from originally – Shamans and Smokers Tobacco - Origin & Consumption

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Nicotine, cotinine (a metabolite of nicotine), and alcohol are not known to cross-react with the test's antibodies

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Its also a concern that people may be unwittingly establishing a tobacco addiction, with cannabis acting as their route into a lifetime of smoking tobacco. The study discusses recent research suggesting that UK-based recreational cannabis users who mix the drug with tobacco will use about 0.35g of tobacco per joint, equivalent to one third of the content of a cigarette

The study also crucially points out that there is no evidence supporting the view that e-cigarettes are a gateway to smoking tobacco, for adults and minors