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In Japan, where there is a unique market for tobacco-related products, reports on the prevalence of e-cigarette and HNB tobacco use are limited to Internet surveys targeting individuals aged over 18 [23]

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Use of spittoons was considered an advance of public manners and health, intended to replace previously common spitting on floors, streets, and sidewalks

The first includes genes with the highest expression in the apical part ( NtZIP2 , NtZIP5A/B, NtIRT1, NtIRT1-like ), the secondthose with the highest expression in the basal part ( NtZIP1-like, NtZIP8 ), the third NtZIP4A/B with the same level in all parts, and the fourth groupgenes with distinct expression in the apical, middle and the basal root part ( NtZIP5-like, NtZIP11 ) (Palusiska et al

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