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Treatment of these ozone-exposed mice with MitoQ (5mg/kg intraperitoneally), an antioxidant that targets the mitochondrion, significantly increased mitochondrial membrane potential and decreased the following: ozone-induced airway hyper-responsiveness, bronchoalveolar lavage total cell counts, keratinocyte-derived cytokine levels, mitochondrial ROS levels and cellular ROS levels 226

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