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Against a backdrop of swirling smoke and crumbling architecture, a symphony of instruments emerges, their notes mingling with the cacophony of destruction to create an otherworldly melody

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Appendix Appendix Search Formulae (July 2020) MEDLINE (PubMed) Keywords: smoking, tobacco, smoking prevention, smoking cessation, smoking cessation aid, nicotine, tobacco use disorder, analgesia, analgesic, and pain. Literature search was conducted in July 2020 using the following formulae: Rights and permissions This article is published under an open access license

This difference likely stems from Ploom's indirect heating method, which appears to gently coax the aromatic compounds from the tobacco rather than extracting them with the intensity of IQOS's direct heating blade

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