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Increased Heart Rate: Nicotine can lead to an elevated heart rate (tachycardia), which can be uncomfortable and concerning

As soon as the pouch is activated, a buzzing sensation is felt in the mouth

In the fully adjusted logistic regression, current e-cigarette use only was associated with lower odds of hypertension than never users (OR 0.77, 95% CI 0.63 to 0.93

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In a case report by Frisland (2017), a newborn, whose mother had reported using large amounts of snus (1020 times/day) during and after pregnancy, showed symptoms of nicotine withdrawal after birth such as continuous crying, sensitivity to light, with high amounts of cotinine in his hair and urine