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The mixture of carcinogens in tobacco smoke causes DNA damage and mutations, promoting tumor development in multiple organs, including the lungs, bladder, and oral cavity

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The guidelines call on enterprises to respect human rights, which means they should avoid infringing on the human rights of others and should address adverse human rights impacts with which they are involved, including by carrying out human rights due diligence and working to remedy adverse human rights impacts they have caused or to which they have contributed