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Consumers place the disposable pouch between their gum and upper lip, typically for around 30 minutes, during which nicotine and flavours are released and the nicotine is absorbed through the oral mucosa
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When comparing the disease phenotypes and outcomes, we did not find any statistical difference between past and current smokers, although high proportions of current and past smokers with CD had strictures and inflammatory disease phenotypes, respectively (Supplementary tables 1 and 2)
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