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Any plant material burned at high temperature releases carbon monoxide (CO), fine particulate matter (PM2.5), polycyclic aromatic hydrocarbons (PAHs), and volatile organic compounds (VOCs).1 A comprehensive review published in Foods (2022) confirmed that herbal cigarettes produce tar and carcinogens at levels comparable to conventional tobacco, despite the absence of nicotine.2 The key combustion byproducts present in all herbal smoke include carbon monoxide, which binds hemoglobin and reduces oxygen delivery to tissues

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The art was primarily religious in nature and depicted deities or rulers smoking early forms of cigarettes

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These researchers used data from smokers and never-smokers and compared it to people who stopped smoking