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Additionally, smoking imposes substantial economic costs on healthcare systems, costing the US around $170 billion in direct cost for medical care and over $156 billion in indirect costs due to productivity loss, including $5.6 billion in lost productivity among nonsmokers who suffer from smoking-attributable conditions because of involuntary exposure to secondhand smoking (Department of Health and Human Services, 2014

Less commonly, clots may form in veins elsewhere in the body

These were normally sold in disposable foil or paper packets, which is why few survive today despite the fact that millions that were produced

Hyperpigmentation of the lips and gums is usually seen in chronic smokers

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