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American variants focus on a blended profile of Burley and Oriental leaves treated with casings, while European brands lean toward intense, darker air-cured tobaccos

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While we know that smoke from cigarettes, bushfires, cooking, vehicle exhausts, and burning waste pose significant health risks, we still surprisingly know relatively little about how the specific components of smoke affect our immune system and how they impact multiple parts of the human body, says co-author of the study David P

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In vitro RNA-seq-based toxicogenomics assessment shows reduced biological effect of tobacco heating products when compared to cigarette smoke