premarket tobacco product applications Perspective: FDA's Progress on Review of Submitted by the Sept. 9, 2020 Deadline FDA's New ENDS and Nicotine

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comparing the acute impact of tobacco versus e-cigarettes with equivalent nicotine content, found that within 5 min of smoking or vaping, both tobacco smokers and healthy individuals exhibited a statistically significant increase in sCD40L, sP-selectin, and platelet aggregation levels in a single-blind crossover trial (40)

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