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Although useful for hypothesis generation and critical for understanding mechanisms of health outcomes, because of important differences such as those pertaining to dose, duration of exposure, and changes in particles and constituents with aging, the relevance of in vitro data for establishing human health risk is uncertain

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A few closing thoughts ENDS have only been available for a decade, so long-term data are not yet available on the potential health implications of vaping

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10.1074/jbc.C200677200