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Signs That Point to Deeper Plumbing Issues Beyond a slow-flushing toilet, watch out for these warning signals indicating more serious problems: Slow drainage not only in the toilet but also in sinks, showers, or tubs Bubbling or gurgling noises coming from pipes during or after flushing Water backing up into other drains when the toilet is used Multiple fixtures blocking up simultaneously, especially during cold weather (possible frozen pipes) Important: Avoid flushing repeatedly to clear the clog, as this risks overflow and water damage

The patient also presented with skin hyperextensibility, joint hypermobility, and Gorlin sign (ability to reach the nose with the tip of the tongue) (Fig

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5 Results 5.1 Demographics and tobacco use Overall, we recruited a total of 604 participants from both Prime Panels and Mturk

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