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Some deregulated genes found in e-cig users, but not in smokers, are nevertheless implicated in lung cancer, esophageal cancer, bladder cancer, ovarian cancer and leukemia

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These symptoms are usually related to the ingredients in the e-liquid, such as propylene glycol, vegetable glycerin, or flavorings, and can be more common in individuals with pre-existing digestive issues or sensitivities

Nicotine pouches must adhere to stringent criteria effective January 1, 2025, including packaging specifications, nicotine concentration limits, and absence of certain additives and stimulants

10.3389/fmicb.2018.03030 79 XingL.YangJ.JiaY.HuX.LiuY.XuH.et al (2021)