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They're not

These may be physical, mental, or a combination

She had her dark secrets and bad habits like other characters on the show, but when push came to shove, she did what was right and frequently helped Mulder and Scully on their quest to expose the truth

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Given that glucose is expected to be completely reabsorbed in the proximal tubule of the kidney [38], these findings could indicate early signs of reduced reabsorption capacity in the proximal tubule of moderate and heavy smokers kidneys