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10.1007/s11553-016-0545-2 57

These patients were then interviewed concerning smoking habits, as were controls selected from patients with other disorders (primarily non-malignant) who were hospitalized in the same hospitals at the same time

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The Nicotine Withdrawal Timeline: Hour by Hour The nicotine withdrawal timeline follows a broadly predictable arc: symptoms begin within 3060 minutes for heavy users, intensify over the first 4872 hours, then gradually ease over two to four weeks