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Symptoms of withdrawal can include: intense cravings increased hunger fatigue lack of concentration headache constipation nausea diarrhea irritability anxiety depression insomnia Your symptoms may be most intense in the first few hours after your last use

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The situation is different for BMS that happens when you have issues like GERD or an oral infection

Increased risk of reproductive problems: Smoking can have adverse effects on both male and female reproductive health

Understanding this process will help in managing expectations regarding timelines and potential amendments that may be needed after submission