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ACS Central Science, 22 February 2023, doi: external page 10.1021/acscentsci.2c01100

29 demonstrated that exposure to 10% cigarette smoke extract had a significant effect on endothelial arginine and proline metabolism, resulting in the reduction of intracellular arginine, N-hydroxy-l-arginine, and citrulline

Limited weight loss First of all, even though smoking increases metabolism, the number of calories burned is too limited to have a significant impact on the smokers weight

DAMAGE FROM SHIPPING: Shipping damage is rare but when it does occur it is usually minor